
two brothers with nephrogenic diabetes insipidus.
the patients, a 5-year-old and a 13-year-old
boy, had suffered from polydypsia
and polyuria since the age of 1 yr.  physical
and mental retardation, hyperchloremia,
and lowering of kidney concentrating power
were observed.  the patients were resistant
to pitressin.  they were considered
to be suffering from nephrogenic diabetes
insipidus caused by a recessive heredity factor.
